Biosyntrx
(800) 688-6815
EpiCor
Immune System Modulator
- Human clinical studies suggest increased humoral B cell salivary IgA and decreased IgE, indicating mucosal immunity.
- Human study indicates rapid increase in serum antioxidant levels and activation of Natural Killer (NK) cells in two or less hours after ingestion.
- In-Vitro and in-vivo studies suggest inhibition of reactive oxygen species formation.
- In-Vitro studies suggest reduced growth of E coli.
- Human studies suggest improved ratio of CD8-T cells to CD4-T cells.
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Human clinical studies suggest significantly shorter cold and flu duration of symptoms when compared with subjects taking placebo.
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EpiCor ORAC value higher than cranberries, blueberries, acai, red wine and pomegranate.
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Recommended dosage: 1 or 2 capsules a day with meals
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90 capsule count per bottle
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Made in the USA toFDA Good Manufacturing Practice Standards
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Sold with full money back guarantee
Know Your EpiCor!
Caveat emptor - Let the buyer beware!
Some "discount" marketers are reported to be selling diluted (cut)
EpiCor as pure. Biosyntrx presents pure EpiCor as a 90 capsule (three month
supply) to best assure product efficacy and consumer compliance.
The EpiCor Story
The extremely low incidence of plant employee health problems in a 63-year-old Iowa company, Diamond V Mills, Inc., coupled with the minimal increases in company health premiums over the years, led researchers to look for potential human health applications of Diamond V's propriety yeast culture designed to keep cattle healthy and increase milk production. Embria Health Sciences, a division of Diamond V, spent more than $1,000,000 to develop a product specifically designed for humans, complete with safety and efficacy studies, before bringing EpiCor to the nutraceutical market.
EpiCor's Composition Assay:
EpiCor is manufactured from a safe, nutrient-dense form of the species of yeast called Saccharomyces cerevisiae through a proprietary multi-stage fermentation and drying process.
The processed yeast includes:
- A variety of macronutrients: lipids, organic acids, complex carbohydrates, including beta glucan, which stimulates macrophage (immune cell) phagocyte activity.
- Eleven (11) micronutrient minerals associated with production of nucleic acid DNA and RNA.
- The entire complex of B vitamins.
- Phytosterols and phenolics plant-based antioxidants associated
with extremely high levels of intracellular and extra cellular activity
(ORAC value higher than blueberries).
Immune System and Eye Disease
Ocular inflammation can produce extensive damage to innocent
bystander cells leading to vision loss and blindness. Fortunately, the
eye possesses multiple strategies to help control immune-mediated
inflammation, a phenomenon known as immune privilege. Nevertheless,
virtually all severe or chronic diseases have, to a greater or lesser
degree, an element of immune dysfunction that is central to the disease
process.
Scientific literature now links many age-related degenerative
diseases of the eye to an autoimmune inflammatory response to external
and internal environmental conditions, including nutritional
deficiencies. These responses include dry eye syndrome, macular
degeneration, glaucoma, diabetic retinopathy, iritis and uveitis.
Immune Modulation Definition:
Immune Modulation Definition:
The process of nutritionally regulating the immune system for optimal functionality. It??s a dynamic process requiring constant support.
Genes, Nutrition and Immune System
Multipotent hemopoietic stem cells (MHSC) are stem cells found in
the human bone marrow. These self-renewing cells are responsible for the
formation of the immune system leukocytes (white blood cells) that
defend the body against infectious disease. Proper development of
theimmune system is dependent on the nutritional status of the body.
This status also affects the macromolecule nucleic acids, including
double helix deoxyribonucleic (DNA) and protein synthesis ribonucleic
(RNA). These are the acids that signal intracellular genetic
instructions responsible for disease susceptibility, including immune
system responses that affect the entire body.
The Immune Cell Community
A properly modulated immune system sends clear instant cellular defense messages that protect the body against viral, bacterial, parasitic and fungal foreign invaders. This is particularly important, given the increased global risk of infection from one of these pathogens.
A properly modulated immune system sends clear instant cellular defense messages that protect the body against viral, bacterial, parasitic and fungal foreign invaders. This is particularly important, given the increased global risk of infection from one of these pathogens.
A healthy immune system is also able to distinguish between the
body??s own cells: self vs. non-self. When the immune system is deficient
in nutritional ammunition, it can send confusing signals that cause it
to turn on itself (autoimmune response). This unleashes a torrent of
inflammatory diseases, including some forms of arthritis, diabetes,
multiple sclerosis, iritis, uveitis, dry eye syndrome, glaucoma and
vascular disease, which contributes to macular degeneration. In other
cases, a malnourished immune system responds to seemingly harmless
foreign substances, resulting in mild or life threatening allergic
response.
Immune System and Eye Disease
Ocular inflammation can produce extensive damage to innocent
bystandter cells leading to vision loss and blindness. Fortunately, the
eye possesses multiple stratefies to help control immune-immediated
inflammation, a phenomenon known as immune privilege. Nevertheless,
virtually all severe or chronic diseases have, to a greater or lesser
degree, an element of immune dysfunction that is central to the disease
process.
Scientific literature now links many age-related degenerative
diseases of the eye to an autoimmune inflammatory response to external
and internal environmental conditions, including nutritional
deficiencies. These responses include dry eye syndrome, macular
degeneration, glaucoma, diabetic retinopathy, uritis and uveitis.
EpiCor Immune Modulation Study Results
In-Vitro Study Results:
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Inhibited formation of reactive oxygen species (ROS) when cells were challenged with hydrogen peroxide.
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Reduced growth of E coli and C tropicallis.
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Inhibited interferon-gamma (IFN-g) production, indicating anti-inflammatory properties. (IFN-g is secreted by overactive T cells and natural killer (NK) cells. Excessive IFN-g can precipitate an autoimmune inflammatory response.)
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Decreased Interleukin-2 stimulation of IFN-g production.
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Increased levels of nuclear factor kappa B (NFkB), which plays an important role in inflammation, immunity, autoimmune response, and cell adhesion, proliferation, development and death (apoptosis) by regulating the expression genes involved in these processes. (This could be particularly important when considering the pathology associated with all chronic degenerative eye disease.)
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Modulated expression of certain adhesion molecules on human NK cells, T cells, B cells and dendrite cells, as well as induced calcium signaling. This is pivotal to cellular coordination response in tissues and organs within the whole body, including the eyes.
Human Study Results:
- Significant (four-fold) increase in Natural Killer (NK) cell cytotoxic activity.
- Changed ratio of CD8-T cells to CD4-T cells. (Manipulation of regulatory T cell populations represents an important approach to immunotherapy of a wide range of immune responses.)
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Increased humoral B cell salivary IgA, indicating that treatment with EpiCor may be associated with development of mucosal immunity.
EpiCor Safety Testing Results
Both
acute (14-day) and sub-acute (90-day) toxicology studies were performed
on EpiCor.
The results:
- Negative for oral toxicity.
- Negative for mutagenicity (AMES Test), and for mitogenicity.
- Free of 139 pesticides at detection limits.
Conclusions:
- Study results indicate that EpiCor is safe, non-toxic, non-mutagenic, non-mitogenic and is pesticide free.
- Pharmaceutical drug metabolism testing suggests no interference from the nutrients in EpiCor.
- Stability tested for a microbiological shelf life of at least 24 months when stored at ambient temperature and humidity.
- EpiCor has obtained generally recognized as safe (GRAS) status.
Other Epicor Reference
Discovery of edible fermentation product with unusual immune
enhancing properties in humans. Schauss A, Vojdani A. The FASEB
Journal 2006;20:A143 [abstract]
Brewer's/baker's yeast (Saccharomyces cerevisiae) and preventive medicine: part 1. Moyad MA, Urol Nurs. 2007 Dec;2796):560-1 [abstract]
Effects of a modified yeast supplement on cold/flu symptoms. Moyad
MA, Robinson LE, et al. Urol Nurs.
2008 Feb;28(1); 50-5 [abstract]
Brewer's/bakers yest (Saccharomyces cerevisiae) and preventive
medicine: Part II. Moyad MA. Urol Nurs.
2008 Feb;28(1):73-5 [abstract]
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QWhy does the EpiCor price vary so much?
Unfortunately, a discount marketer has purchased some EpiCor and is selling it far under market price. The contents of the inexpensive product looks nothing like the real thing. These products are, most likely, cut with fillers, which is most unfortunate because pure EpiCor is an exceptional immune system modulator.
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QWhat are CD-4 and CD-8 cells?
These are white blood cells that have been activated by the thymus - therefore they are known as T-cells. CD-4 cells are helper T- cells. They coordinate the activities of our immune system. Once activated, they divide rapidly and secrete small proteins called cytokines that signal the immune system to take action. People with CD-4 counts around 500 usually have fairly normal immune function and are at low risk for opportunistic infections. Current U.S. government guidelines recommend that you should consider HIV treatment when your CD-4 count falls below 350 cells. People with CD-4 cell counts below 200 are diagnosed as having AIDS. The guidelines recommend starting treatment at this point, if you have not already done so. As the CD-4 count goes down, HIV persons are more likely to develop opportunistic infections and cancers. CD
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QHave the EpiCor study results been published?
EpiCor studies have been published in a number of peer-reviewed journals.
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QDoes EpiCor prevent colds and flu?
FDA dietary supplement regulations prevent companies from making health claims on dietary products. Compliant EpiCor users (those who take it everyday as recommended) are reporting extremely low incidence of colds or flu.
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QCould EpiCor cause yeast infections?
Nutritional yeasts are not live yeast cells. Saccharomyces cerevisiae, the type of nutritional yeast included in EpiCor has been dried at temperatures high enough to render it inactive, therefore it is not associated with systemic yeast infections, vaginal yeast infections, or thrush.
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QAre there any adverse EpiCor side effects?
No adverse side effects have been reported.
