ZoOmega-3

ZoOmega-3

ZoOmega-3

Concentrated Pharmaceutical-Grade Fish Oil

  • Molecularly distilled for high concentration of EPA and DHA
  • Supports healthy triglyceride levels
  • 60 capsule count per bottle
  • Recommended dosage: 1 capsule per day with meals on days oily fish is not included in diet.   
  • Guaranteed to be mercury and PCB free
  • Made in the USA to FDA Good Manufacturing Standards (GMP).  
  • Full Money Back Guarantee - without exception
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ZoOmega-3 Product Information

Each capsule of ZoOmega-3 contains a 50% concentrate of pure pharmaceutical-grade oil from cold water fish. It is stabilized with 5 IUs of alpha tocopheryl Vitamin E and is guaranteed to contain no discernible amount of mercury, PCBs, cholesterol or triglycerides.
 
We always recommend that all fish oil capsules be consumed with a full-spectrum multiple that provides adequate antioxidants to address the metabolic oxidative stress associated with the retinal pigment epithelial (RPE), because it is one of the most active tissues in the body, and it includes the highest amount of Omega-3 DHA.

One capsule of ZoOmega-3 includes 300 mg of eicosapentaenoic acid (EPA) and 200 mg of docosahexanoic acid (DHA).  Each bottle of ZoOmega-3 contains 60 capsules. The recommended dosage is one capsule on days fish is not consumed as part of a daily diet.



ZoOmega-3 Condition Overview

Years of over-consumption of overly processed foods (mostly junk) has made the U.S. the least healthy country in the industrialized world. Fortunately for us, sufficient amounts of parent omega-3s as ALA or omega-3 EPA and DHA mostly from fish can help balance, or neutralize some of the effects from the oils included in ALL processed cakes, cookies, chips, crackers, muffins, bagels, donuts, rolls, most breads and all fried foods.

However, popping excessive fish oil capsules does not mean that you can continue to consume large amounts of processed junk food and  expect to stay healthy.

Scientific Rationale for ZoOmega-3

Small published studies support some fish oil supplementation because it contains the omega-3 essential fatty acids (EFAs), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). These long-chain fatty acids are precursors to eicosanoids (site specific hormones, also referred to as signaling molecules) that reduce inflammation throughout the body including the eyes.

The long chain omega-3 fatty acids, EPA and DHA can be synthesized  from plant- based omega-3 fatty acid alpha-linoleic acid (ALA), but EPA and DHA synthesis from ALA is limited. The capacity for conversion of ALA to DHA is higher in women than men. 

In a scientific statement called Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease, the American Heart Association stated, "The EPA and DHA form of omega-3 can have a therapeutic role in the treatment of very high triglycerides, and both EPA and DHA have triglyceride-lowering properties." (3)
  • There is now some factual basis from laboratory and clinical trials that omega-3 fatty acids may help prevent fatal arrhythmias in animals and humans. (3)

  •  EPA and DHA is suggested in some studies to prevent or slow the progression of many degenerative diseases associated with elevated plasma levels of triglycerides. (3)

  • Long chain Omega-3 fatty acids and vitamin A palmitate are suggested to slow the progression of Retinitis pigmentosa. (4)

  • Primary open-angle glaucoma patients are suggested to have reduced levels of blood EPA and DHA. (5)

    Regulation of Gene Expression

The results of cell culture and animal studies indicate that omega-6 GLA and omega-3 fatty acids EPA /DHA can modulate the expression of a number of genes, including those involved with fatty acid metabolism and inflammation. (13-14)

References:

 

1. Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men. Burdge GC, Jones AE, et al. Br J Nutr. 2002;88(4):355-364 [abstract]
2. Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. Burdge GC, Wootton SA. Br J Nutr. 2002;88(4):411-420 [abstract]
3. Anti-arrhythmic properties of N-3 poly-unsaturated fatty acids (n-3 PUFA). Lombardi F, Terranova P. Curr Med Chem 2007;14(19):2070-80 [abstract]
4. Retinitis pigmentosa. Hartong DT, Berson EL, Dryja TP Lancet 2006 Nov 18;368(9549):1795-809. [abstract]
5. The role of omega-3 long-cahin polyunsaturated fatty acids in health and disease of the retina.SanGiovanni JP, Chew EY. Prog Retin Eye Res. 2005 Jan;24(1):87-138 [abstract]
6. Cell survival matters: docosahexaenoic acid signaling, neuroprotection and photoreceptors.Bazan NG, Trends in Neurosciences 2006
7. Neuroprotection D1 (NPD10): a DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress. Bazan NG.Brain Pathol. 2005 Apr;15(2):159-66 [abstract]May;29(5):263-71 [abstract]
8. Application of nutrigenomics in eye health. Delcourt C. Forum Nutrition 2007;60:168-75 [abstract]
9. Photoreceptor outer segment phagocytosis attenuates oxidative streee-induced apoptosis with concomitant neuroprotectin D1 synthesis. Mukherjee PK, Marcheselli VL, et al. Proc National Acad Sci 2007 Aug 7:104(32):13158-63 [abstract]
10. Increased dietary intake of omega-3 polyunsaturated fatty acids reduces pathological retinal angiogenesis. Connor KM, SanGiovanni JP, Lofqvist C, et al. Nat Med 2007Jul;13(7):868-73 [abstract]
11. Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection. Bazan NG Curr Opin Clin Nutr Metab Care 2007 Mar;10(2):136-41 [abstract]
12. TOZAL Study: an open case control study of an oral antioxidant and omega-3 supplement for dry AMD Cangemi FE BMC Ophthalmol 2007 Feb 26:7:3 [abstract]
10. Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection. Bazan NG Curr Opin Clin Nutr Metab Care 2007 Mar;10(2):136-41 [abstract]
13.Inhibition of cytokine signaling in human retinal endothelial cells through modification of caveolae / lipid rafts by docosahexaenoic acid. Chen W, Jump DB, et al. Invest Ophthalmol Vis Sci. 2007Jan;48(1):18-26 [abstract]
14. Effects of EPA, DHA on the secretion of NO, expressions of iNOS mRNA and DNA-binging activity of NFkappyB in human monocyte Xia Y, Feng X, Chen Y, SuY, Wei Sheng Yan Jiu 2007 Jul;36(4):445-8 [abstract]